Description
Usage: All products on this site are for In-Vitro Research, Development use only. Products are Not for Human consumption of any kind.
Data
Name: Tirzepatide
CAS No.: 2023788-19-2
PubChem CID: 156588324
IUPHAR/BPS: 11429
DrugBank: DB15171
ChemSpider: 76714503
UNII: OYN3CCI6QE
KEGG: D11360
ChEMBL: ChEMBL4297839
Formula: C225H348N48O68
Molar mass: 4813.527 g·mol−1
Other Names: LY3298176, GIP/GLP-1 RA
Purity: 98.5%min
Brand Name: UNEWLIFE
Grade: Pharm Medicine Grade
MFG: each batch fresh in 2023
Shelf Life: 2 years of proper storage
Appearance: White Powder
Test Reports: MS/COA/HPLC
Packing: 10mg*10vials/box
Label: without labels, can be OEM/ODM customized.
Box: white carton box, that can be OEM/ODM customized.
Shipping: by express or post.
Feedback: How do they say? More reviews here
For more questions, check the answers here: FAQ
Description
Tirzepatide is a first-in-class medication that activates both the GLP-1 and GIP receptors, which leads to improved blood sugar control.
Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are hormones involved in blood sugar control.
Tirzepatide is indicated to improve blood sugar control in adults with type 2 diabetes, as an addition to diet and exercise.
Mechanism of action
Tirzepatide is an analogue of gastric inhibitory polypeptide (GIP), a human hormone that stimulates the release of insulin from the pancreas. Tirzepatide is a linear polypeptide of 39 amino acids that has been chemically modified by lipidation to improve its uptake into cells and its stability to metabolism. It completed phase III trials globally in 2021.
Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behavior has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist. Signaling studies have shown that this is due to tirzepatide mimicking the actions of natural GIP at the GIP receptor. However, at the GLP-1 receptor, tirzepatide shows bias towards cAMP (a messenger associated with regulation of glycogen, sugar and lipid metabolism) generation, rather than β-arrestin recruitment. This combination of preference towards GIP receptor and distinct signaling properties at GLP-1 suggest this biased agonism increases insulin secretion.
Tirzepatide has also been shown to increase levels of adiponectin, an adipokine involved in the regulation of both glucose and lipid metabolism, with a maximum increase of 26% from baseline after 26 weeks, at the 10 mg dosage.
Mario (verified owner) –
This I go to tirzepatide!
Claire (verified owner) –
I have tried some Tirzepatide but the test went really bad. This one is good, it seems like it is authentic.
Carolyneb (verified owner) –
I have never been so impressed with this before.It is much helpful. I would recommend tirzepatide to anyone looking to transform their health!
Enineone (verified owner) –
It has transformed my life in so many ways. I was wary of weight loss medications in the past but tirzepatide proved me wrong. The weight has been dropping off, my joints don’t ache anymore and I feel years younger. Customer service has been exceptional
saint01152 (verified owner) –
Good for brands-building
Zenaida (verified owner) –
Works great
Beautycap (verified owner) –
10 bottles one box! I was delighted by the affordability of the product without compromising on its quality. The company’s communication was transparent and timely, keeping me informed at every stage. The product has exceeded my expectations in terms of efficacy.
Joan Spencer (verified owner) –
The payment process was such a challenge because they only accepted CRYPTO. But you know me, I was determined to get it! I took the time to educate myself and persisted until I successfully completed the payment. Thanks UNEWLIFE team, they gave me a tutorial which I learned a lot and trusted them then, but during the order processing, I was a ball of nerves, constantly wondering if the parcel would actually make it to me. But guess what? My worries melted away when the package arrived right on time! It didn’t disappoint! The product’s functionality was absolutely amazing, and I was thrilled with how well it performed. Seriously, despite the initial payment difficulty, all the effort was totally worth it because this product delivers!
Matt Middendorf (verified owner) –
Comparable to other vendor’s product for a great price.